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The Australian Diabetes Society and Australian and New Zealand College of Anaesthetists have released statements advising routine cessation of SGLT-2 inhibitors during the perioperative period to reduce this risk

In general, the safety profile of semaglutide injection 2.4mg in SELECT aligned with earlier trials

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At higher concentrations, cocaine also blocks different voltage gated channels in a state-dependent manner with a higher affinity for inactivated and open states vs rested/closed states of the channels

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