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The prevailing model for NRF2-dependent target gene expression involves the binding of NRF2 to ARE sequences within proximal promoters of specific target genes (Tonelli et al, 2018)

It is particularly beneficial for those with a body mass index (BMI) of 30 or higher or a BMI of 27 or higher with weight-related health conditions such as diabetes or high blood pressure

Some of these infection-linked chronic symptoms overlap or exacerbate ones caused by conditions that can come with obesity, such as depression

Some people continue requiring ongoing management strategies throughout treatment

However, your provider will need to review your complete medical history and current medications to ensure it's safe and appropriate for you

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