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When we talk about the miracle of blockbuster medications like Ozempic and Wegovy, we are discussing substances designed to mimic this precise natural process

But that approach would need to be trialed and tested, McCoy says

GLP-1 receptor agonists and GLP-1/GIP combination therapies have become foundational treatments for type 2 diabetes and obesity

This controlled and consistent drug delivery also helps reduce systemic side effects by eliminating peak concentrations on bolus (injection) administration

Multiple studies demonstrate that when people stop using these medications, they regain most of the weight lost within a few months unless they have made diet and lifestyle changes