Knockdown of CD36 led to only a modest reduction in the protective effect (Supplementary Fig
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[DOI] [PMC free article] [PubMed] [Google Scholar] 246.Chrisnasari R., Hennebelle M., Vincken J.P., van Berkel W.J.H., Ewing T.A
In contrast, CYP2E1 is found in many tissues in addition to the liver, including the brain, heart, lungs, neutrophils, and macrophages
No evidence it causes cancer but could feed existing cancer
Response: As readers are aware, we have been contemplating potential clinical APC assignments for the past number of rulemaking cycles but are not convinced as to what clinical APC would be appropriate in terms of clinical and resource homogeneity