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Response: We thank the commenter for underscoring the importance of the time from Decision to Transfer (order) to the ED departure, one of the numerator components for the measure

Consequently, it remains one of the most compelling peptides in metabolic and obesity research today

indicated that the peptide reduced over 50% of body weight gain in these laboratory models compared to controls, with heightened lipolytic activity observed within the adipose tissues of exposed rats, alongside an absence of notable disruptions in insulin sensitivity in these experimental settings

The peptide was synthesized using solid-phase methods and purified via reverse-phase high-performance liquid chromatography (HPLC)