While the test focuses on peptide genetic variants (including GLP1R, GIPR, FTO, and MC4R polymorphisms), these same genetic factors influence overall metabolic efficiency, insulin sensitivity, and antioxidant enzyme expressionall relevant to whether ALA or glutathione supplementation warrants consideration
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Reznikov, Vladimir A
A randomized, placebo-controlled study in 52 subjects (mean age, 30 years) with relapsing-remitting multiple sclerosis found an increase in total antioxidant capacity in blood with lipoic acid supplementation (1,200 mg/day for 12 weeks) yet not in the activity of specific antioxidant enzymes (superoxide dismutase and glutathione peroxidase) (97)
doi: 10.1161/ATVBAHA.120.315267 204 NotzQ.HerrmannJ.SchlesingerT.HelmerP.SudoweS.SunQ.et al
Annu Rev Biochem 1983
