GAPS recognizes the connection between the functions of the digestive system and the brain
suggests that a key element in this process involves the activation of G-proteins, which are closely associated with the inner surface of the cell membrane and activate downstream pathways leading to the production of secondary messengers such as cyclic adenosine monophosphate (cAMP) and inositol triphosphate (IP3)
While this evidence is promising, researchers emphasize the importance of larger, more definitive studies to confirm these effects and establish optimal dosing and treatment durations
Li N, Neu J (2009) Glutamine deprivation alters intestinal tight junctions via a PI3-K/Akt mediated pathway in Caco-2 cells
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