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Picomolar to nanomolar activity suggests high receptor affinity and potent biological signalling, which is encouraging for topical delivery where only a fraction of applied compound reaches the follicle

Figure 2: Changes in A) SOD activity, B) total GSH, C) IL-6 levels in BALF, and D) TNF-alpha levels in BALF across the treatment groups in response to varying doses of GHK-Cu

Proposed therapeutic mechanism for this include, blocking inflammation by modulating endoplasmic reticulum stress and neutralising free radicals, it may also help protect against the effects of covid by inhibiting SARS-CoV-2 by delivery of curcumin to bind to the S-protein, ACE2 receptor

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Certain vegetables and fruits, such as tomatoes, pineapples, and cucumbers, have moderate glutathione content, approximately 12-33 mg/100g, while foods like sweet potatoes, mung bean sprouts, onions, and shiitake mushrooms have lower levels, only 0.06-0.7 mg/100g

To compare the frequency difference between groups, the chi-squared test or Fischers exact test was used