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Jan Versijpt, orcid.org/0000-0002-8710-5715

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Furthermore, tirzepatide demonstrates enhanced affinity for GLP-1R relative to native GLP-1, while simultaneously engaging the GIP receptor, thereby amplifying its therapeutic efficacy in glycemic control and weight reduction (Fig

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It serves to reduce cholesterol, improve insulin function to enhance the metabolism of fats and facilitate the proper functioning of serotonin which regulates your moods and your appetite

This design ensures spatial separation of the GLP-1 N-terminus from the albumin moiety, preserving receptor-binding capacity and maintaining full biological activity