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The dose itself might not change dramatically from the systemic protocol (e.g., 250-350mcg total per day), but the location of the administration is the key variable

The peptide demonstrates protective effects against gastric ulceration, promotes healing of intestinal lesions, and modulates gut inflammation through multiple pathways

Moreover, in contrast to asthma and COPD, where enhanced SubP and/or tachykinin signaling is potentially pathogenic, a decrease in SubP-mediated secretion in CF might be of detriment [99]

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