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Managing gastrointestinal side effects, particularly nausea, requires a multifaceted approach that may include both behavioral modifications and potential medical interventions

Mild GI discomfort (nausea, bloating) is occasionally reported, particularly at higher doses [1][29]

Ros S, Santos CR, Moco S, Baenke F, Gavin Kelly G, Howell M, Zamboni N and Schulze A

Goitrogens, compounds found in these vegetables, primarily interfere with thyroid function only in excessive raw quantities or with iodine deficiency

RNA isolation, cDNA synthesis, and qRT-PCR analysis Total RNA was extracted from lettuce shoots and roots using TRIzol reagent (Invitrogene, USA) according to the manufacturers guidelines and clarified from DNA contamination utilizing DNase enzyme

Additionally, older adults may have chronic conditions or take medications that further impact nutrient absorption and utilization