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A 2024 study in Cardiovascular Diabetology found that those who retained 6% or more of their pre-pregnancy weight by five years after giving birth face higher risks of pre-diabetes, unhealthy cholesterol levels, and other early markers of heart disease

From this perspective, the MD represents a particularly suitable strategy for patients undergoing pharmacological therapy with GLP-1 RAs such as semaglutide

As an antiGDF8 myostatin inhibitor , it binds directly to this signaling molecule and limits its biological activity

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HLPC-grade acetonitrile and methanol were obtained from Fisher Scientific (Leicester, UK) and used without further purification

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