Some community members prefer a more conservative approach starting at 1mg
Author's Note: This article reflects my personal experience and should not be interpreted as medical advice
Its a meaningful improvement for overall cardiovascular risk even if the absolute number doesnt shift dramatically
Mechanism of Action GLP-1 agonists exert their effects through multiple mechanisms, all of which contribute to their therapeutic benefits
"Food could potentially remain in the stomach longer, increasing the risk of aspiration and pneumonia if it enters the windpipe during procedures." In response to these concerns, the American Society of Anesthesiologists recommended that patients discontinue GLP-1 agonists at least seven days before any surgery or endoscopy
Conversely, in gout, reduced bile acid levels lead to diminished TGR5 activity, which in turn results in reduced GLP-1 secretion, and weakened inhibition of both the NF-B pathway and NLRP3 inflammasome