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This is not a reason to change medication

WHO is currently working on a rapid advice guideline on possible use of GLP-1 RAs, including semaglutides, for treatment of obesity in adults and as part of a more comprehensive model of care

That said, some patients do experience mild stimulant-like effects from the bupropion component, including increased energy, reduced appetite, and occasionally insomnia

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These effects occur without elevating IGF-1 or affecting carbohydrate metabolism, differentiating it from full-length HGH in terms of safety and selectivity

Semaglutide is a safe and effective treatment when used for FDA licensed indications