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One notable example of the progress in VitC pre-clinical research is the recent work in hard-to-treat Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) driven tumours, such as KRAS mutant colorectal cancer (CRC) [25, 27, 32]

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Also, if there are low levels of cysteine in cells during times of oxidative stress, this may limit their ability to make their own glutathione