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The hormone insulin plays a crucial role in promoting the uptake of glucose in adipose and muscle tissue, as well as in synthesizing glycogen in muscle and secreting triglycerides ( As illustrated in Figure 1, MetS is associated with an elevation in oxidative stress, which is the underlying cause of various complications such as atherosclerosis, hypertension, myocardial infarction, and inflammation

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The inclusion criteria were (1): original research articles, clinical trials, meta-analyses, and comprehensive reviews relevant to the topic

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However, no preclinical study has directly compared the cognitive effects of PXN and CAF supplementation