FDA Filing Review (~60 Days Later): The FDA determines whether to accept the application for formal review and assigns a target decision date (PDUFA)
Because it is a large, sequence-defined molecule, the usefulness of any given lot depends on precise synthesis, purification, and storage
Regardless of which category is used, results vary from person to person and tend to be strongest when peptide therapy is paired with a healthy diet, regular exercise, and consistent habits
Other minor data points made by Lilly included that patients on retatrutide had an average systolic blood pressure reduction of 14mmHg
During this initial period, monitor how you feel and maintain adequate hydration
Discontinuation Rates Discontinuation rates due to adverse events in the Phase 2 trial were dose-dependent, ranging from approximately 6% in the 1 mg arm to 16% in the 12 mg arm