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Functionally, in the SLC30 family, ZnT1 functions primarily as a zinc exporter on the cell membrane, transporting cytoplasmic zinc ions across the membrane to the extracellular space, while other ZnT proteins are situated on the membranes of intracellular organelles

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Rapamycin , an mTOR inhibitor used as an immunosuppressant that extends lifespan in several animals, has no brain-specific human evidence