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For example, before the price decreases, the cost of GLP-1 receptor agonists had been compared to bariatric surgery, with GLP-1s representing an ongoing monthly expense while surgery involves a high upfront cost

If hyperglycemia is not controlled during surgery, osmotic diuresis may occur, resulting in excessive loss of fluids and electrolytes

March 10, 2025

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Regulatory agencies have previously found unlicensed weight loss treatments containing banned drugs like Sibutramine (a heart-risk stimulant removed from the market)

The post hoc analysis of pooled data from the Semaglutide Treatment Effect in People with Obesity (STEP) 1, 2, 3, and 5 trials indicated that semaglutide treatment at 2.4 mg did not increase the risk of depressive symptoms or suicidal ideation compared to placebo, while demonstrating a statistically significant yet clinically negligible decrease in depressive symptoms [75]