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The resolutions of the final consensus maps were 2.2 , 2.2 , 2.7 and 3.0 for the CTR, AMY 1 R, AMY 2 R and AMY 3 R, respectively, determined at gold standard Fourier shell correlation (FSC) 0.143 (Fig
Detection, characterization, and decay kinetics of ROS and thiyl adducts of mito-DEPMPO spin trap
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It is naturally synthesized within the cytosol of almost every cell in the body, with the highest concentrations found in the liver, lungs, and brain
2016;14:e1002516
Mechanistically, they promote the translocation of Ahr into the nucleus, where it competes with hypoxia-inducible factor (HIF)-1 for binding to the Ahr nuclear translocator (ARNT), thus inhibiting HIF-1-mediated cardioprotective effects like NO and vascular endothelial growth factor (VEGF) production (Li W
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