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In humans and mice, GLP-1 is predominantly amidated, whereas in rats both amidated and nonamidated GLP-1 is present (1,2)

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This is supported by preclinical and some early clinical data

According to Dr Henrik Gudbergsen, the researcher who presented the Danish study: A patients appetite returns when they stop taking the drug, and if they stop taking it suddenly, they may find it hard to resist their cravings

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