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Acral lentigines may be influenced by genetic factors, since they are frequently found in darkly pigmented individuals

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Cuarto, al mejorar el metabolismo de cidos grasos y reducir la acumulacin de intermediarios lipdicos en clulas endoteliales, puede reducir la activacin de vas inflamatorias como NF-B que suprimen la expresin de xido ntrico sintasa e incrementan la expresin de molculas de adhesin proinflamatorias

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