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In the nigrostriatal tract system, dopamine undergoes autooxidation or oxidative deamination by monoamine oxidase-B, both of which aggravates with age, leading to increased production of peroxides and hydroxyl radicals 41

The metal chaperone Atox1 regulates the activity of the human copper transporter ATP7B by modulating domain dynamics

To extend stability, peptide solutions are often stored in sterile buffers with a pH around 56 and kept at -20C or colder when appropriate

By targeting the Carnitine Shuttle and hepatic lipid export pathways, it allows scientists to investigate the fuel supply side of bioenergetics

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& Tremblay, J.P