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What Side Effects Are Relevant to Research Models Involving These Compounds In clinical research populations, both compounds share a gastrointestinal adverse event profile consistent with incretin-based mechanisms: nausea, vomiting, diarrhoea, and constipation are the most commonly reported effects, typically dose-dependent and most prominent during dose escalation [2][5]

Keywords: Alzheimers disease, GLP-1 receptor agonist, hippocampus, liraglutide, memory function, neuroprotection, SAMP8 mouse, stereology INTRODUCTION Alzheimers disease (AD) is a common neurodegenerative disease being the leading cause of dementia-associated morbidity and mortality in the elderly population, affecting more than 25 millionpeople worldwide [1]

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