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Zweck E, Hepprich M, Donath MY

Variants in the GLP1R gene (including rs6923761) and GIPR gene (rs1800437) influence how your body processes semaglutide and how sensitive your skin and immune cells are to GLP-1 activation

PLoS One 7 , e45748 (2012)

In fact, beyond their metabolic benefits, GLP-1 RAs have been shown to influence key neural circuits involved in reward and addictive behaviors