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Severe hypoglycemia causes confusion, difficulty speaking, loss of consciousness, or seizures and constitutes a medical emergency requiring immediate professional care

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doi: 10.7573/dic.212283 [DOI] [PMC free article] [PubMed] [Google Scholar] 32

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Anaphylaxis with semaglutide is rare but documented [4]

It suggests HbA1c, fasting glucose, insulin, a lipid profile, and inflammatory markers such as CRP to contextualize response potential