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In vitro , liraglutide dose-dependently downregulates pro-inflammatory mediators such as Mcp-1 and Cd38 in LPS-activated RAW264.7 macrophages, while simultaneously upregulating Erg-2, an M2-specific transcription factor (Yu et al., 2019)

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In a randomized, double-blind and controlled trial, 90 patients supplemented with Que twice daily for 12 weeks showed significantly higher erythrocyte levels but evidently lower mean erythrocyte volume and hemoglobin, as well as ferritin compared to controls (77)

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