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Its amino acid sequence and structural characteristics provide some resistance to degradation

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The three best-characterized sites within the mitochondrial respiratory chain are complexes I, II, and III, located in the inner mitochondrial membrane

Like it was unofficial or unproven, but as Voss explained, off-label doesnt mean unsafe, just that the treatment is being used in a way not originally specified in its FDA approval, and after seeing before-and-after photos, I decided to try it

Witham MD, Nadir MA, Struthers AD