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However, as prescription of semaglutide and similar medications escalated, anecdotal reports of reduced alcohol use became very common, and suggested the potential of these more potent therapies for treatment of alcohol use disorder. While the findings are promising, the researchers still need to determine exactly how semaglutide reduces alcohol cravings

"Glucose-dependent insulinotropic polypeptide receptor-expressing cells in the hypothalamus regulate food intake." Cell Metabolism , 30(5), 987-996

Staying relaxed during injection also reduces muscle tension, which can amplify perceived discomfort

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How long does it take to regain weight after stopping semaglutide