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State-by-state implementation will vary

This mechanism leverages the natural vulnerability of fat cells to sustained cold temperatures

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Anaesthetists may use gastric ultrasound, rapid sequence induction, or extended clear-fluid diets to manage aspiration risk

Early months (months 13) typically show slower loss due to titration

Nonetheless, these trials collectively give clinicians confidence that using sitagliptin or other DPP-4 inhibitors to treat hyperglycemia will neither cause nor prevent cardiovascular events on average, so other cardioprotective strategies must be employed in tandem