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There are a wide variety of active peptides that include antioxidant peptides and opioid peptides that have important neuroprotective effects

In cisplatin-induced renal toxicity, gastrodin inhibits ferroptosis through SIRT1/FOXO3A/GPX4 signaling pathway and protects the kidney from damage (Qiu et al., 2024)

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PI3K then rapidly phosphorylates Akt in primary neurons, initiating Akt-dependent inhibition of FoxO1 activity