retatrutide dosage trials Dosing Guide: 1-12 mg Weekly Triple Agonist (2026) Retatrutide Dosage: Titration Schedule |

SURMOUNT-1 tirzepatide 15 mg reported roughly 22.5% at 72 weeks [4]

doi: 10.1111/dom.15538 [DOI] [PubMed] [Google Scholar] 171.Oneil PM, Aroda VR, Astrup A, et al

TRIUMPH-4 (Phase 3, 68 weeks) 12mg dose: 28.7% weight loss (~71 lbs / 32 kg average) 9mg dose: 26.4% weight loss (~64 lbs / 29 kg average) Patients also saw 76% reduction in knee osteoarthritis pain Blood pressure reduced by 14 mmHg on average Source: ClinicalTrials.gov (TRIUMPH-4, NCT05931367) The TRIUMPH Phase 3 program includes 4 trials studying retatrutide for obesity, type 2 diabetes, and cardiovascular outcomes

And if they do help you, you may have to take them indefinitely or risk regaining most of the weight you lost

This supports muscle preservation and skin health

Furthermore, reductions in the incidence of cardiovascular events have also been evidenced 19