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Long-term use of proton pump inhibitors and metformin can impair B12 absorption, necessitating monitoring or parenteral therapy
Afterward, 100 mcg must be injected continuously throughout your life for the best results
PMC Article PMC12446177
B12 injections may be a good option if you are feeling unusually fatigued, following a restricted diet, taking medications that can reduce B12 absorption, or looking for added wellness support as part of a broader health and aesthetic plan
In some cases you may need a higher dose, such as 25 to 50 micrograms daily, but this should be determined by your doctor if youre supplementing to treat symptoms
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