Anesthesiology 112 , 226238 (2010)
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This is not the same as proving short-term IGF-1 LR3 use causes cancer in healthy adults it is a real biological-mechanism concern that supports cycle limits and absolute contraindication in anyone with cancer history
Nonetheless, individual variability and formulation discrepancies may affect safety profiles
238 , 239 , 240 In addition, studies have found that people with a history of TBI who develop dementia do so at a younger age than those without a history of TBI
However, human clinical trials are still limited, and optimal dosing in humans has not been formally established