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REDEFINE 4: The Tirzepatide Test The results that attracted the greatest market attention came from REDEFINE 4, an 84-week open-label Phase 3 trial reported in February 2026, in which CagriSema was pitted directly against tirzepatide 15 mg, the highest approved dose of Eli Lillys Zepbound

Luckily, my GP was much better informed - and where a referral proved useless, would redirect me elsewhere

[1] [2] Important tirzepatide warnings include potential reduced efficacy of oral contraceptives during initiation and dose increases

Yan, M., Hernandez, M., Xu, R., & Chen, C

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