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While inhaled corticosteroids like budesonide can have minimal systemic absorption, the risk of decreased bone mineral density is primarily associated with long-term, high-dose use rather than short-term or intermittent rescue use of Airsupra

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For short-term storage (a few weeks), a standard refrigerator (2C to 8C or 36F to 46F) is perfectly fine

Sirvi et al., 1987

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Many researchers establish a rotation pattern, moving systematically between sites