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However, synaptic disturbances has been observed in early stages of the tauopathy in animal models (Hoover et al., 2010) and tau oligomers proposed as the toxic conformational state of the protein (Lasagna-Reeves et al., 2011)

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Source: New England Journal of Medicine

W., Luengo, A., Mayers, J

Tarumi Y, Wilson MP, Szafran O, Spooner GR