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Targeting these amino acid-driven metabolic circuits may offer novel therapeutic opportunities in fibrotic diseases such as IPF, where metabolic vulnerabilities can be exploited to disrupt fibroblast activation and excessive ECM remodeling

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Other statistical analyses were conducted, and forest plots created using Stata software (version 16.0, Stata Corp., College Station, TX)

Shared decision-making : If considering offlabel or prevention use, open discussion of uncertain benefit, possible side effects, cost, monitoring is essential

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