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Los estudios preclnicos sugieren una interaccin funcional con los receptores GABA-A, aunque el mecanismo molecular preciso requiere mayor investigacin

In a mouse model, piperine effectively alleviated allergic symptoms, including sneezing and nasal rubbing, and reduced inflammatory markers, including histamine, IgE, IL-6, IL-1, and NO levels

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A total of 10 studies were identified from the literature for inclusion in the systematic review (Figure 1)