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Historically, peptides have been recognized for their diverse roles as hormones, signaling molecules, carriers, and supplements

In pregnant women with epilepsy who take ASMs, perinatal folic acid use is associated with better cognitive development in their children, as reflected by their Full-Scale Intelligence Quotient at 3 and 6 years of age (34)

found higher amounts of salivary irisin in obese individuals with PWS compared to non-obese controls, while plasma levels of irisin did not show significant changes between the two groups (93, 94)

This modulation may lead to better-supported subperiosteal bone formation, resulting in a potential increase in bone dimensions without necessarily altering the intrinsic volumetric mineral density

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doi: 10.1016/j.envexpbot.2017.06.008 111 WeiC.JiaoQ.AgathokleousE.LiuH.LiG.ZhangJ.et al