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Management strategies include smaller frequent meals, texture modifications, adequate hydration, and gradual dose titration under medical supervision

This triple agonism strategy builds upon the remarkable clinical success of dual GLP-1/GIP agonists like tirzepatide, which have shown unprecedented weight loss efficacy, by adding a third mechanism - glucagon receptor activation - to further enhance metabolic benefits, particularly energy expenditure and hepatic fat oxidation

Tirzepatide SURMOUNT trials: raising the bar Then came the SURMOUNT trials

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