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Arginine consumption also impaired the function of CD8 + T cells due to proline synthesis and ornithine, a non-protein amino acid, secretion

Beyond improving right ventricular function and mitigating pulmonary vascular remodeling, HUC-MSCs extensively suppress the infiltration of pulmonary macrophages (both M1 and M2 subtypes) and the expression of related inflammatory cytokines, reduce the recruitment and activation of immune cells such as T cells (Oh et al., 2021)

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Most mitochondrial proteins are encoded by nuclear DNA, and specific N-terminal tags allow importation of proteins across the inner membrane, as well

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