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Local administration is commonly used because its effects appear strongest close to the target tissue

Cirrhotic human liver extracellular matrix 3D scaffolds promote smad-dependent TGF-1 epithelial mesenchymal transition

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GLP-1 and alcohol in animal models GLP-1R activation has been shown to reduce alcohol consumption, alcohol reward, and motivated alcohol seeking

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Co-cultures of brain endothelial cells with astrocytes, pericytes, neurons, or microglia or some combinations have also been widely explored using transwell inserts