Topical and systemic cannabidiol improves trinitrobenzene sulfonic acid colitis in mice
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More serious but less common risks include acute pancreatitis, gallbladder disease, and dehydration-related acute kidney injury
Finally, the analysis of the predicted metabolites revealed that AcM could enhance the production of microbial molecules related to lipid-metabolism, active metabolites and neurotransmitters (valeric/isovaleric acid, azelate, azelaic acid, anandamide C20:4, carnitine and undecanedioic acid), metabolism of vitamins and nucleotides/nucleosides, whilst possibly depleting inosine
Two natural products, (-)-Vestitol and Salviolone, were selected for further validation