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Ther Adv Psychopharmacol

Tirzepatide: Zepbound and Mounjaro Tirzepatide is a dual GIP/GLP-1 receptor agonist, meaning it works through two pathways instead of one

In clinical trials, these medications led to a 15 to 20% reduction in body weight when paired with a reduced-calorie diet and regular exercise

This is an important limitation because temporary surface plumping is not the same as structural volume restoration

1mg weekly (conservative community approach) or 2mg weekly (Phase 2 trial protocol)

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