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We downregulated the expression of genes related to the GSH metabolic pathway in VRK2-KO PC cells and examined their effects on cellular viability, ROS and GSH

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Persistent activation of the hypothalamic-pituitary-adrenal (HPA) axis, the bodys primary neuroendocrine stress-response system, has been linked to anxiety, depression, fatigue, cognitive impairment, metabolic dysfunction, cardiovascular disease, and accelerated biological aging [15]

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EPS often requires higher concentrations to be effective in some cell lines, such as MCF7, than in HT-29 cells (Jenab et al., 2020)