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Identifying the Strong Response Endotype For the study, researchers conducted a secondary analysis of data from a previous clinical trial of tirzepatide in patients with OSA and obesity

FDA extended the review time period by 90 days

While human GLP-1R expression occurs primarily in cardiomyocytes, murine cardiac Glp1r expression remains confined to endocardial cells [2]

Effects in mice and rats do not reliably predict effects in humans, and animal dosing does not translate directly

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