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This coordinated release scheme is reminiscent of neuromodulatory D-serine co-transmission at NMDA receptors, and may even suggest co-release of D-serine and polyamines from astrocytes under these conditions (with the caveat that D-serine gliotransmission is controversial) (Figure 2

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5-Oxoproline as a cause of high anion gap metabolic acidosis: an uncommon cause with common risk factors

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