Nature 540 (7634), 544551
Other drugs which have been found to be of little or no value in withdrawal trials over 4-6 weeks include buspirone (BuSpar, an anti-anxiety drug), carbamazepine (Tegretol, an anticonvulsant), clonidine (Catapres, an anti-anxiety drug sometimes used in alcohol detoxification), nifedipine (Adalat) and alpidem
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[4] The interaction between Epithalon and the SIRT1/SIRT6 sirtuin-mediated chromatin deacetylation pathway which plays a documented role in telomere maintenance and DNA repair warrants investigation given the mechanistic overlap at the chromatin level