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These agents also suppress glucagon secretion from pancreatic alpha cells, further helping to lower blood glucose levels

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3.3 Long-acting GLP1 receptor agonists: Once-weekly 3.3.1 Semaglutide SMG is an analog of long-acting GLP-1, mainly used to control T2DM, and is also suitable for promoting weight loss in people with mild obesity (95, 96)

Hydration is also important because prolonged nausea accompanied by vomiting or diarrhea can contribute to volume depletion